Dresden 2017 – wissenschaftliches Programm

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DY: Fachverband Dynamik und Statistische Physik

DY 25: Posters - Soft Particles, Microswimmers, Microfluidics

DY 25.2: Poster

Dienstag, 21. März 2017, 18:15–21:00, P3

Tracking of PEG nanoparticles flowing around red blood cells inside microchannels — •François Yaya, Thomas John, and Christian Wagner — Experimental Physics, University of Saarland

During their life span in our body, red blood cells (RBC) travel through capilaries within a few microns in diameter. In this study, we reproduce these conditions using microfluidic chips with microchannels. Microchannels of 10 µm are built in polydimethylsiloxane (PDMS). Blood was drawn from a single donor from the fingertip and RBC were washed by standard protocol in a solution of Phosphate Buffered Saline (PBS) in which they were resuspended. Nanoparticles of polyethylene glycol (PEG) with a diameter of 250 nm were added at different concentrations. We use a high speed camera to record the particles flow at different pressure drops, flow velocities respectively, to monitor the particles displacements. We track these particles by image processing and we analyse the particles’ trajectory. We show the behaviour of PEG nanoparticles around the RBC in different reference frames and different conditions (e.g. concentration, pressure). We give an overview on the parameters having an influence on the flow, vorticity and the nanoparticles distribution around the RBC.