Berlin 2018 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 21: Microswimmers (joint session BP/CPP/DY)

BP 21.5: Vortrag

Mittwoch, 14. März 2018, 16:15–16:30, H 1028

Applying an Extended Kalman Filter to extract bacteria statistics — •Oliver Köhn — Universität des Saarlandes

Bacteria tend to swim in liquids in absence of food facilitated by creation of flagella. The trajectories are determined by slightly curved lines (running states) and randomly interrupted by short intervals with strong direction changes (tumbling state)[1]. This behavior seems to be efficient in finding food in unknown environments. We assume an intrinsic randomness in the running states as well in the appearance of the tumbling intervals.[1] Furthermore in real experiments the extracted positions are influenced by a detection noise. Estimating the stochastic trajectory properties requires the distinction between bacteria intrinsic randomness and the measurement noise. From the engineers it is known that the Kalmann filter algorithm provide this in an optimal way [2]. We adapted and implemented this filter for simulated as well as measured bacteria trajectories.

[1] Enhancing bacterial motility and search efficiency by genetic manipulation of flagellar number; Javad Najafi, M. Reza Shaebani, Thomas John, Florian Altegoer, Gert Bange & Christian Wagner; submitted to PNAS [2] Forecasting, structural time series models and the Kalman filter; Andrew C. Harvey; 1989; Cambridge University Press