Berlin 2018 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 27: Cell Mechanics II

BP 27.6: Vortrag

Donnerstag, 15. März 2018, 11:30–11:45, H 1028

Simulations of stem cells in microjets — •Carina Bezold, Christian Bächer, and Stephan Gekle — Biofluid Simulation and Modeling, Bayreuth, Germany

3D bioprinting offers the opportunity to create tissues and organs which could be used for transplantation. The tissue is built up layer for layer by a continuous jet containing stem cells.We develop a model for stem cells as elastic spheroids, using tools of the finite element method. We validate our model using the Hertzian theory for small deformations. To simulate the fluid, we use 3D Lattice-Boltzmann simulations including the transition from the printer nozzle into the free liquid jet. This region is of particular interest since high extensional forces are present. Due to the different flow profiles at the transition we observe a change in the cell shape.