Berlin 2018 – wissenschaftliches Programm
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MA: Fachverband Magnetismus
MA 15: INNOMAG e.V. Diploma-/Master Prize 2018
MA 15.1: Hauptvortrag
Montag, 12. März 2018, 16:55–17:15, H 0112
Magnetic particle mapping with magnetoelectric sensors for characterization of bioscaffolds — •Ron-Marco Friedrich1, Sebastian Zabel1, Jan-Martin Wagner1, Christine Selhuber-Unkel2, and Franz Faupel1 — 1CAU Kiel, Institute for Material Science, Chair for Multicomponent Materials, Kaiserstr. 2, 24143 Kiel, Germany — 2CAU Kiel, Institute for Material Science - Biocompatible Nanomaterials, Kaiserstr. 2, 24143 Kiel, Germany
Bioscaffolds for cell growth have great potential in the area of medical life science. The characterization of the scaffolds with regard to the cell growth needs to meet certain objectives to ensure non-invasiveness and non-destructiveness. Here, a novel detection method for magnetically labeled cells using magnetoelectric (ME) sensors is introduced where, similar to magnetic particle imaging (MPI), the nonlinear magnetization behavior of magnetic particle ensembles is used to detect higher harmonic excitations. The ME sensor consists of a piezoelectric and magnetostrictive thin film on a freestanding cantilever, which shows a sharp mechanical resonance and anisotropy in its sensitivity. This leads to a selective signal acquisition with respect to the spatial orientation of the sensor and the applied excitation frequency. Thus, by moving the sensor over a sample, we can locally detect higher harmonic excitations and create a map of the magnetic field of the magnetic particles. We describe the abilities of the detection system and create a forward simulation of this kind of imaging system to reconstruct the particle distribution.