Würzburg 2018 – wissenschaftliches Programm

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ST: Fachverband Strahlen- und Medizinphysik

ST 5: Biomedical Imaging II

ST 5.2: Vortrag

Mittwoch, 21. März 2018, 16:45–17:00, Phys-HS P

X-ray dark-field imaging of porcine lung tissue in different Talbot-Lau setups — •Veronika Ludwig¹, Katharina Hellbach², Michael Gallersdörfer¹, Christian Hauke¹, Florian Horn¹, Georg Pelzer¹, Marcus Radicke³, Jens Rieger¹, Maria Seifert¹, Sven-Martin Sutter³, Thilo Michel¹, and Gisela Anton¹ — ¹ECAP Medical Physics Group, Friedrich-Alexander-University Erlangen-Nürnberg, Germany — ²Institute of Clinical Radiology, Ludwig-Maximilians-University Hospital Munich, Germany — ³Siemens Healthcare GmbH, Erlangen, Germany

Grating-based X-ray phase-contrast imaging provides the differential phase and the dark-field image, in addition to the conventional attenuation image. Lung tissue consists mainly of air-filled alveoli, such that the porous structure formed by many air-tissue-boundaries leads to a strong dark-field signal. Therefore, X-ray dark-field imaging seems to be a promising method for the diagnosis of lung diseases, while conventional X-ray imaging often lacks the required contrast. Aiming at the investigation of the different origins of dark-field contrast discussed in literature, we measured the same porcine lung using different interferometer setups. They differ by grating periods and inter-grating distances while the system-specific components focal spot size, magnification and detector pixel size are maintained. Furthermore, our measurements show that lung diagnosis by X-ray phase-contrast imaging is also feasible with large grating periods at a low dose.