Regensburg 2019 – wissenschaftliches Programm
AKjDPG 3: PhD Focus Session: Theory of Stochastic Processes with Applications in Biology (joint session SOE/BP/DY/AKjDPG)
AKjDPG 3.2: Vortrag
Donnerstag, 4. April 2019, 15:45–16:00, H17
Thermodynamics of steady-state switching — •Jacob Cook1,2 and Robert G. Endres1,2 — 1Department of Life Sciences, Imperial College, London, UK — 2Centre for Integrative Systems Biology and Bioinformatics, Imperial College, London, UK
Entropy production is a hallmark of nonequilibrium processes in stochastic thermodynamics. Multistable nonequilibrium systems are abundant outcomes of nonlinear dynamics with feedback yet relatively little is known about what determines the stability of the steady states and their switching rates in terms of entropy and entropy production. Here, we will link the fluctuation theorem for the entropy production along trajectories and the large-deviation approach of minimum-action-path theory to elucidate the thermodynamics of steady-state switching. Interestingly, we find that the entropy production at steady state plays no explicit role, but the entropy production along switching trajectories is key. Alternative stabilising and destabilising mechanisms such as steady-state entropy and diffusive noise are also investigated.