Regensburg 2019 – wissenschaftliches Programm
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MA: Fachverband Magnetismus
MA 51: Magnetism Poster B
MA 51.17: Poster
Donnerstag, 4. April 2019, 15:00–18:00, Poster C
Magnetoimpedance biosensor for detecting stray fields of nanoparticles: experiment and model — •Elizaveta Golubeva1, Benjamin Spetzler2, Franz Faupel2, and Galina Kurlyandskaya1 — 1Ural Federal University, Ekaterinburg, Russia — 2Kiel University, Kiel, Germany
Magnetic nanoparticles (MNPs) offer great potential to be involved in a wide range of biomedical applications. One of the main challenges for the utilization of MNPs is their detection and precise localization in a patient's body. Magnetic field sensors based on the giant magnetoimpedance effect (GMI) are promising candidates for detection, due to potentially large sensitivities [1] and small detection limits [2]. However, a compromise must be reached between an optimum magnetic bias field for GMI sensitivity and the maximum net stray field of the MNPs. With this work, a comprehensive model is presented that describes the mutual interaction of the sample and the sensing element as well as the resulting electrical impedance. The model is used to find the optimum operation parameters for the sensor, including the geometric and magnetic configuration of the system. Finally, the results are compared with measurements on sensor prototypes with an amorphous wire or a ribbon as a sensitive element. General consequences are derived.
[1] N.A. Buznikov, et al., Biosensors and Bioelectronics, 117,366-372, (2018) [2] T. Uchiyama, et al., Physica Status Solidi (a), 206, 639-643, (2009)
This work is supported by the RSF grant 18-19-00090.