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Dortmund 2021 – wissenschaftliches Programm

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ST: Fachverband Strahlen- und Medizinphysik

ST 1: Radiation Therapy

ST 1.5: Vortrag

Montag, 15. März 2021, 17:00–17:15, STa

Investigation of radio-activation of titanium implants in proton therapy — •Fleur Anna Spiecker1, Claus Maximilian Bäcker1,2,3,4, Christian Bäumer2,3,4, Walter Jentzen4, Sandra Kazek4, Kevin Kröninger1, Beate Timmermann2,3,5, and Jens Weingarten11TU Dortmund, Experimentelle Physik IV, 44227 Dortmund — 2Westdeutsches Protonentherapiezentrum Essen, 45122 Essen — 3Westdeutsches Tumorzentrum, 45122 Essen — 4Universitätsklinikum Essen, 45122 Essen, Klinik für Nuklearmedizin — 5Universitätsklinikum Essen, Klinik für Partikeltherapie, 45122 Essen

In order to verify the calculated proton dose distribution after the proton irradiation of a patient, the β+ activation of titanium implants can be used. For this purpose, the knowledge of the dependence between the dose, activity and proton energy is needed.

To examine this dependence, different PMMA phantom shapes with different titanium implants are irradiated with protons and measured over time with a PET scanner. The results are illustrated as depth activation curves and compared with the depth dose curve, which is calculated by the treatment planning system. To verify the dose, the expected activity is calculated as a function of depth by using the cross sections of the positron-emitting reaction products. The local proton energies are calculated by using the CSDA-ranges for water and titanium. With this method the distal fall-off of the activity distribution can be already predicted successfully for a simplified setup. In this talk the results of the project will be presented.

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