Dortmund 2021 – wissenschaftliches Programm
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ST: Fachverband Strahlen- und Medizinphysik
ST 1: Radiation Therapy
ST 1.7: Vortrag
Montag, 15. März 2021, 17:30–17:45, STa
Evaluation of a New Inverse Planning Software and Implementation of Plan Verification for Gamma Knife Treatments — •Feline Heinzelmann1, Moritz Budde2, Kevin Kröninger1, and Jan Boström3 — 1Technische Universität Dortmund, Experimentelle Physik 4, Dortmund, Germany — 2Marien Hospital Herne, Universitätsklinikum der Ruhr-Universität Bochum, Klinik für Strahlentherapie und Radio-Onkologie, Herne, Germany — 3Gamma Knife Zentrum, Bochum, Germany
Gamma Knife therapy uses ionizing radiation for stereotactic radiosurgery. This non-invasive treatment is suitable for brain diseases, such as malignant and benign brain tumors or vascular malformations. Usually, radiation treatment plans are created either manually or with the help of an optimization software of the Gamma Knife device manufacturer. This inverse planning software often converges to local minima of the objective function precluding the optimal solution.
The software IntuitivePlan uses a new global convex optimization algorithm. In a prospective user study, this algorithm was tested in clinical practice and was evaluated based on plan quality metrics.
In particular, the use of the plan optimization software shows a considerable improvement in the selectivity of the target volume and high target volume coverage. Significant differences are likewise apparent in the planning time and the sparing of organs at risk. Further advantages and disadvantages, especially concerning the disease, were identified. Preparations to implement a treatment plan verification for Gamma Knife radiosurgery by using film dosimetry have been made.