SurfaceScience21 – wissenschaftliches Programm
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O: Fachverband Oberflächenphysik
O 14: Poster Session I: Nanostructures at surfaces I
O 14.5: Poster
Montag, 1. März 2021, 10:30–12:30, P
Electrospray Ion Beam Deposition of Biological Molecules — •Henrik Siboni1,2, Andreas Zimmer2, and Leonhard Grill1 — 1Single-Molecule Chemistry, Institute of Chemistry, University of Graz, Austria — 2Pharmaceutical Technology & Biopharmacy, Institute of Pharmaceutical Sciences, University of Graz, Austria
Scanning Tunneling Microscopy under Ultra-High Vacuum (UHV) conditions is a powerful method to image single molecules. However, its application in biophysics and pharmacy is limited by the fact that thermal sublimation, which is the common deposition method under UHV, requires rather high temperatures, due to the large molecular mass and thus low vapour pressures. This typically leads to molecular fragmentation before they can adsorb on a surface. Drop casting, on the other hand, can leave too much solvent contamination. In this poster, electrospray ion beam deposition of biological molecules will be presented where the molecules are gently transferred from solution under atmospheric pressure to a single-crystal metal surface at UHV pressure.