SKM 2023 – wissenschaftliches Programm
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BP: Fachverband Biologische Physik
BP 28: Poster Session II
BP 28.40: Poster
Donnerstag, 30. März 2023, 18:00–20:00, P2/EG
Coordination of information in Physarum polycephalum — •Kaspar Wachinger1, Johnny Tong1, Nico Schramma2, Siyu Chen1, and Karen Alim1 — 1School of Natural Sciences, Technical University of Munich, Germany — 2Faculty of Science, University of Amsterdam, The Netherlands
Physarum polycephalum is a network-structured, single-cell organism with thousands of nuclei that can sense and adapt to its environment. To understand how P. polyephalum maintains efficient gene expression, it is necessary to understand the coordinated intracellular transport of nuclei within its structure. Microinjecting several fluorescent dsDNA markers into the tubes of P. polyephalum allows in-vivo imaging of nuclei and their dynamics: Nuclei can either be trapped in the more solid wall cortex or follow the oscillatory cytoplasmic streaming. We investigate the flow-driven behaviours of nuclei in functionally different regions of P. polycephalum’s network and motivate a hypothesis of inter-nuclei communication far past the degradation distance of mRNA.