SKM 2023 – wissenschaftliches Programm
DY 45.6: Poster
Donnerstag, 30. März 2023, 13:00–16:00, P1
Advection dependent pulse dynamics — •Adrian Misselwitz1, Susanne Lafon2, Jean-Daniel Julien2, and Karen Alim1,2 — 1School of Natural Sciences, Technische Universität München — 2Max-Planck-Institut für Dynamik und Selbstorganisation, Göttingen
Models of pulse formation in nerve conduction have provided manifold insight not only into neuronal dynamics but also the non-linear dynamics of pulse formation in general. Recent observation of neuronal electro-chemical pulses also driving mechanical deformation of the tubular neuronal wall and thereby generating ensuing cytoplasmic flow now question the impact of flow on the electro-chemical dynamics of pulse formation. We, here, theoretically investigate the classical Fitzhugh-Nagumo model now accounting for advective coupling between the pulse propagator typically describing membrane potential and here triggering mechanical deformations and, thus, governing flow magnitude, and the pulse controller, a chemical species advected with the ensuing fluid flow. Employing analytical calculations and numerical simulations we find, that advective coupling allows for a linear control of pulse width while leaving pulse velocity unchanged. We therefore uncover an independent control of pulse width by fluid flow coupling.