SKM 2023 – wissenschaftliches Programm
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MA: Fachverband Magnetismus
MA 36: Magnetic Particles / Clusters
MA 36.3: Vortrag
Donnerstag, 30. März 2023, 10:00–10:15, HSZ 401
High throughput analysis of surface-functionalized superparamagnetic particles in dynamic magnetic field landscapes — •Yahya Shubbak1,2, Rico Huhnstock1,2, Kristina Dingel2,3, Bernhard Sick2,3, and Arno Ehresmann1,2 — 1Institute of Physics & Center for Interdisciplinary Nanostructure Science and Technology (CINSaT), University of Kassel, D-34132 Kassel — 2AIM-ED - Joint Lab Helmholtzzentrum für Materialien & Energie, D-14109 Berlin — 3Intelligent Embedded Systems, University of Kassel, D-34121 Kassel
The precise manipulation of magnetic micro- and nano-particles in microfluidic environments opens new avenues for investigations of biomolecular analyte detection and interactions.[1] Motion control schemes based on a combination of static magnetic field landscapes superposed with external magnetic field pulses enable translatory motion control of magnetic particles at the nanoscale over macroscopic distances.[3] Here we demonstrate a novel method harnessing AI-enhanced fully-automated optical recognition algorithms [4] to analyze changes in the motion behaviour of such particles due to liquid mediated surface to surface (particle to substrate) interaction.
[1] Lim, B., Vavassori, P., Sooryakumar, R. & Kim, C. Nano/microscale magnetophoretic devices for biomedical applications. J. Phys. D: Appl. Phys. 50, 33002 (2017) [2]Lin, G., Makarov, D. & Schmidt, O. G. Magnetic sensing platform technologies for biomedical applications. Lab on a chip 17, 1884-1912 (2017) [3]Issadore, D. et al. Magnetic sensing technology for molecular analyses. Lab on a chip 14, 2385-2397