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ST: Fachverband Strahlen- und Medizinphysik

ST 1: Accelerators for Radiation Therapy (joint session ST/AKBP)

ST 1.4: Talk

Tuesday, March 21, 2023, 11:45–12:00, GER/038

Dose Simulation of Ultra-High Energy Electron Beams for Novel FLASH Radiation Therapy Applications — •Kelly Grunwald, Klaus Desch, Daniel Elsner, Dennis Proft, and Leonardo Thome — Physikalisches Institut der Universität Bonn

The electron stretcher facility ELSA delivers up to 3.2 GeV electrons to external experimental stations. In a new setup the irradiation of tumor cells inside a water volume with doses of up to 50 Gy by ultra-high energy electrons (UHEE) in time windows of microseconds up to milliseconds (FLASH) is currently investigated. This technique may enable highly efficient treatment of deep-seated tumors alongside optimal sparing and protection of healthy tissue. Along the effort to measure the dose with a suitable detector, our approach is to determine the optimal dose distribution by simulations. Therefore, the electromagnetic shower process is simulated in Geant4, taking the extracted electron pulse properties into account. A virtual water volume is constructed of voxels of different sizes for precise investigation in the volume of interest. Various properties such as particle types, deposited energy and the energy spectra of the particle shower can be extracted and correlated to relative and absolute dose measurements at the real water phantom. The method and first results will be presented.