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BP: Fachverband Biologische Physik
BP 26: Biomaterials and Biopolymers (joint session BP/CPP)
BP 26.1: Vortrag
Donnerstag, 12. März 2026, 09:30–09:45, BAR/SCHÖ
Characterization and Application of Honey-PVA Electrospun Scaffolds in Tissue Engineering — •Catalina Navarrete-Vera1, Karen Yáñez2, Cristian Acevedo2, and Tomas Corrales1,2 — 1Departamento de Física, Universidad Técnica Federico Santa María, Valparaíso, Chile — 2Centro de Biotecnología Daniel Alkalay Lowitt, Universidad Técnica Federico Santa María, Chile
Tissue engineering seeks to develop functional biomaterials that integrate seamlessly with biological systems. Electrospinning with static collectors enables the production of nanostructured scaffolds suitable for cell regeneration (10.1021/acsomega.3c06436). Incorporating natural components, such as honey, valued for its regenerative, anti-inflammatory, and antimicrobial properties, offers a route to bioactive wound-dressing alternatives (10.1016/j.carbpol.2019.05.004).
In this study, Manuka and Ulmo honeys were each combined with PVA to generate nanofibers and scaffolds via electrospinning. AFM force spectroscopy was used to assess individual fiber mechanics, and SEM and cell-culture assays were employed to evaluate morphology and biocompatibility. Both formulations produced fibers of similar diameter (100-300 nm) and nanomechanical stiffness (~200 MPa), while honey-containing scaffolds improved cell growth over controls. These results indicate that Ulmo honey is a promising alternative to Manuka honey for tissue-engineering applications.
Keywords: Tissue Engineering; Biomaterials; Mechanical Propperties; Cell Culture; Honey