Dresden 2026 – wissenschaftliches Programm
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BP: Fachverband Biologische Physik
BP 31: Focus Session: Theoretical Modeling and Simulation of Biomolecular Condensates II (joint session CPP/BP)
BP 31.1: Vortrag
Donnerstag, 12. März 2026, 11:30–11:45, ZEU/0260
Exponential Size Control in Biomolecular Condensates via Universal Scaling of Power-Law Distributions — •Yifan Huang1, Chuan Tang1, Haoyu Song2, Bing Miao3, and Qiyun Tang1,4 — 1Key Laboratory of Quantum Materials and Devices of Ministry of Education, School of Physics, Southeast University, Nanjng 211189, China — 2School of Physics, Zhejiang University, Hangzhou 310058, China — 3Center of Materials Science and Optoelectronics Engineering, College of Materials Science and Opto-Electronic Technology, University of Chinese Academy of Sciences, Beijing 100049, China — 4Jiangsu Physical Science Research Center, Nanjing 210093, China
Power-law distributions are ubiquitous phenomena in diverse systems, whereas concomitant scale invariance hinders the exploration of precise size control for biocondensates in recent experiments. Using massive computer simulations and the kinetic theory of coalescence, we demonstrate that the cutoff volume can collapse all power-law distributions of biocondensates in different parameters onto one master curve. Remarkably, the cutoff size can increase exponentially by increasing monomer concentrations R∼ eφ, of which nanometer condensates in simulations can be extrapolated to micrometer droplets in experiments. The findings provide a new mechanism to rapidly tailor the biocondensates to appropriate sizes through power-law distributions, which can stimulate explorations in biological and other nonequilibrium systems
Keywords: Size Control of Biocondensates; power-law distribution; exponential growth