Dresden 2026 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 7: Poster Session I

BP 7.52: Poster

Montag, 9. März 2026, 15:00–17:00, P5

Quantifying vascular morphology on a chip — •Leonie Karr — TUM, Munich, Germany

Our human vasculature is dynamic, growing and reorganising not only in development but also continuously adapting its morphology. Yet, what determines vessel formation and branching in healthy and disease states seems complex, given the multitude of contributing factors. Our focus lies in growing a human vasculature within the controlled environment of a chip, with the goal of quantifying the flow properties of self-organised in vitro networks. Employing image analysis techniques in conjunction with flow simulation methods, our objective is to accurately quantify how flow and related properties, such as shear stress and absorption determine network architecture. The results obtained from our analyses will significantly contribute to the development of next-generation therapeutics aimed at targeting vessel development.

Keywords: fluid dynamics; on-chip vasculature