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Q: Fachverband Quantenoptik und Photonik

Q 82: Matter Wave Interferometry, Metrology, and Fundamental Physics IV

Q 82.7: Vortrag

Freitag, 6. März 2026, 16:00–16:15, P 11

Towards matter-wave interferometry of proteins — •Olga Rybakova¹, Josef Reisinger¹, Amal S. Kumar², Valentin Köhler², Marcel Mayor², Stefan Gerlich¹, Philipp Geyer¹, and Markus Arndt¹ — ¹University of Vienna, Faculty of Physics & Vienna Doctoral School of Physics Boltzmangasse 5, 1090 Wien, Austria — ²University of Basel, Department of Chemistry St. Johanns-Ring 19, 4056 Basel, Switzerland

In recent years, our team has provided experimental evidence for the wave nature of tailored organic molecules with masses up to 25 kDa, as well as for that of vitamins and antibiotic polypeptides. We now aim to step our studies up to a significantly higher level of molecular complexity by enabling matter-wave interference with genuine proteins.

Achieving this goal requires coordinated advances on several technological fronts, including generation of stable, slow, and cold molecular beams, coherent manipulation of complex particles, and, potentially, their detection in a neutral state. In this contribution, we outline our approach toward enabling protein interferometry and present recent progress on implementing a molecular beam splitting mechanism based on specially designed photocleavable tags.

Keywords: Matter Wave interference; Photocleavable molecules; Protein science