Regensburg 2007 – wissenschaftliches Programm

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CPP: Fachverband Chemische Physik und Polymerphysik

CPP 3: Colloids and Nanoparticles I: Structure

CPP 3.8: Vortrag

Montag, 26. März 2007, 12:00–12:15, H47

Smart Multifunctional Hybrid Microgels for Biological Applications — •Jorge Rubio-Retama, Nikolaos Zafeiropoulos, and Manfred Stamm — Leibniz-Institute für Polymerforschung e.V. Dresden

In summary, a simple chemical route to synthesize multifunctional smart microgels for bio-applications is discussed in the present study. Magnetic iron oxide nanoparticles were incorporated on the surface of P(NIPAM-AA) microgels rendering materials which are both magnetically and thermally responsive. SEM analysis revealed that the composite microgels have a dense "raspberry" type morphology, whilst TEM and SAED confirmed the presence of cubic gamma-Fe2O3 nanoparticles mostly on the surface of the microgels. SQUID experiments corroborated the results of SAED showing that indeed the iron oxide nanoparticles are superparamagnetic cubic gamma-Fe2O3. The incorporation of the iron oxide on the P(NIPAM-AA) microgels shifted their volume transition temperature from 36 to 40 °C, yielding a material that is biocompatible and potentially well suited as carrier for controlled drug release.