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BP: Fachverband Biologische Physik
BP 26: Posters II
BP 26.19: Poster
Thursday, February 28, 2008, 17:00–19:30, Poster A
Carbon Coated Nanomagnets for Biomedical Applications — •A.U.B. Wolter1, Y. Krupskaya1, C. Mahn1, S. Hampel1, D. Haase1, A. Leonhardt1, A. Vyalikh1, A. Werner2, A. Taylor2, K. Krämer2, B. Büchner1, and R. Klingeler1 — 1Leibniz Institute for Solid State Research, IFW Dresden, 01069 Dresden, Germany — 2Universitätsklinikum Carl Gustav Carus, 01307 Dresden, Germany
There is a rapidly increasing interest in applying carbon nanotubes (CNT) in biomedicine since they can be filled with tailored material, thereby acting as chemically and mechanically stable nanocontainers. Furthermore, the carbon shells enhance the possibilities for exohedral functionalization, this way targeting e.g. pathological tissue. We report on a systematic approach to exploit the potential of filled CNT to act as magnetic nano-heaters, temperature sensors and contrast agents which allow a diagnostic and therapeutic usage on a cellular level. Here, we present a detailed field and frequency dependent study of different concentrations of Fe-filled CNT suspensions, which imply their potential for magnetic nano-heaters in a hyperthermia cancer treatment. Indeed, there is a substantial temperature increase of Fe-CNT under applied AC magnetic fields. Furthermore, filled CNT can also be used for diagnostic purposes such as contrast agents in MRI or for the simultaneous detection of the resulting temperature increase, since the nanocontainers can be filled with (additional) appropriate sensor materials. An example is their filling with copper or silver halides, which exhibit a strongly temperature dependent NMR signal so that nanoscaled contactless temperature sensors are realised.