Berlin 2008 – wissenschaftliches Programm
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ST: Fachverband Strahlen- und Medizinphysik
ST 4: Poster Session Radiation and Medical Physics
ST 4.3: Poster
Montag, 25. Februar 2008, 16:30–17:00, H 2033
Atmospheric plasma jet for medical application — Antje Lehmann1, Ulrich Dussa2, Thomas Arnold1, •Georg Boehm1, Axel Schindler1, and Stefan Rupf2 — 1Institut für Oberflächenmodifizierung e.V., Permoserstrasse 15, 04318 Leipzig, Germany — 2Universitätsklinikum des Saarlandes, Klinik für Zahnerhaltung, Parodontologie und Präventive Zahnheilkunde, 66421 Homburg/Saar
During the last decade non-thermal plasma jets have been emerged as a versatile technology for surface processing like local etching, deposition, surface cleaning and surface activation. We have developed atmospheric plasma jets on the basis of 2,45 GHz microwave discharges for medical and for dentistry applications. The present investigation is aimed to operate the jet to deactivate bacteria. A mixture of He, N2 and O2 (1000 sccm : 500 sccm : 4 sccm) was used for driving the jet and to produce oxygen radicals and/or ozone. The average microwave power of 1.6 W has been adjusted to avoid jet temperatures above 40∘C. Thus, thermal effects to the bacteria should be excluded. In the first experiments to treat bacteria films a glass object holder was coated with sterilized Escherichia coli film of about 100 µm thickness. After an exposure time of 30 s a destruction of the cell layer has been observed at a spot size of about 2 mm in diameter. The results demonstrate the non-thermal effect of the destruction of the bacteria by the plasma jet which is potentially applicable to human bodies. Further experiments utilizing living cells in vitro are under way to confirm these results. Here the influence of different treatment parameters is regarded.