Regensburg 2010 – scientific programme

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BP: Fachverband Biologische Physik

BP 4: Statistical Physics of Biological Systems II (joint BP, DY)

BP 4.6: Talk

Monday, March 22, 2010, 15:45–16:00, H45

The first passage problem for diffusion through a cylindrical pore with sticky walls — •Nicholas A. Licata^1,2 and Stephan W. Grill^1,2 — ¹Max Planck Institute for the Physics of Complex Systems, Dresden, Germany — ²Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

We calculate the first passage time distribution for diffusion through a cylindrical pore with sticky walls. A particle diffusively explores the interior of the pore through a series of binding and unbinding events with the cylinder wall. Through a diagrammatic expansion we obtain first passage time statistics for the particle's exit from the pore. Connections between the model and nucleocytoplasmic transport in cells are discussed.