Regensburg 2010 – scientific programme

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BP: Fachverband Biologische Physik

BP 5: Posters: Biopolymers and Biomaterials

BP 5.32: Poster

Monday, March 22, 2010, 17:15–20:00, Poster B1

Biomimetic Modelling of Cellular Morphogenesis — •Björn Stuhrmann, Feng-Ching Tsai, and Gijsje Koenderink — FOM Institute AMOLF, Amsterdam, The Netherlands

Migration and division of living cells are ultimately generated by the coupled morphogenesis of the cell cytoskeleton and the plasma membrane. Despite impressive advances in the identification of the cell molecular inventory, the underlying processes are still poorly understood. We strive to discern biophysical principles of cytoskeletal and cell morphogenesis. To this end, we construct a biomimetic model system of the cytoskeleton by confining to liposomes cross-linked actin biopolymers driven by the active processes of polymerization and motor sliding. The key innovation of this project lies in its systematic biomimetic approach alongside quantitative morphological and mechanical examination and theoretical modelling.