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Regensburg 2010 – wissenschaftliches Programm

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DY: Fachverband Dynamik und Statistische Physik

DY 12: Soft Matter I

DY 12.2: Vortrag

Dienstag, 23. März 2010, 14:45–15:00, H47

Mechanical Properties of Bilayer Membrane and Inclusion — •Giovanni Marelli — Institut für theoretische Physik Friedrich-Hund-Platz 1 D-37077 Göttingen

The presence of a hydrophobic inclusion in a bilayer membrane modifies the shape and the mechanical properties of the membrane. Due to the surface tension between the inclusion and the hydrophobic monomers the region around the inclusion is enriched in chains and the membrane bends around the defect. After the enriched zone the membrane is deplected and is prone to the formation of a pore. In this talk is presented a coarse-grained solvent-free model to study polymersome/nanoparticle and lipid vesicle/peptide inclusions. In the first system, we investigate the condition of stability of the nanoparticle with and without the presence of defectants that decrease the surface tension of the inclusion. In the second one the attention is placed upon to the radial profile of the bending of the membrane around the peptide, which is compared to a continum elastic model, to the increase of the membrane tension and to the packing effect of the lipids around the peptide.

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