Hannover 2013 – wissenschaftliches Programm
Bereiche | Tage | Auswahl | Suche | Aktualisierungen | Downloads | Hilfe
MO: Fachverband Molekülphysik
MO 19: Poster 2: Biomolecules, Cold Molecules, Experimental Techniques, Various Topics
MO 19.19: Poster
Mittwoch, 20. März 2013, 16:00–18:30, Empore Lichthof
Nanosecond T-Jump experiments in small proteins - a circular dichroism study — •Andreas Steinbacher2,1, Lucille Mendonça1, and François Hache1 — 1Laboratoire d’Optique et Biosciences, École Polytechnique/CNRS/INSERM, 91128 Palaiseau cedex, France — 2Institut für Physikalische und Theoretische Chemie, Universität Würzburg, Am Hubland, 97074 Würzburg
The folding dynamics of small proteins has been studied within a nanosecond T-jump experiment. Employing a new experimental set-up based on the frequency-quadrupling of an 82 MHz Titanium-Sapphire laser rapid CD measurements could be performed. By combining time-resolved absorption and circular dichroism in the deep UV, we are able to measure precisely the unfolding relaxation time as well as the helical fraction evolution of peptides and proteins to infer information on their biological function.