Regensburg 2013 – wissenschaftliches Programm
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BP: Fachverband Biologische Physik
BP 18: Membranes and Vesicles I
BP 18.7: Vortrag
Mittwoch, 13. März 2013, 11:30–11:45, H44
Interbilayer repulsion force from coarse-grained simulations — •Yuliya Smirnova1, Volker Knecht2, and Marcus Müller1 — 1Georg August University, Institute for Theoretical Physics, Göttingen, Germany — 2University of Freiburg, Institute of Physics, Freiburg, Germany
Using the coarse-grained MARTINI model of POPC lipids and water [1] we study interactions between bilayer membranes with and without external forces applied to the system. Upon dehydration the bilayer structure changes differently: without external forces, the membrane thickness increases; with an external force acting on the center of mass of the bilayers, however, membranes laterally stretch. We find that in both cases the interbilayer forces decay exponentially with slightly different decay lengths and substantially different pre-exponential coefficients. We propose a way to estimate hydration repulsion between lipid bilayers from both simulations and our results for the disjoining pressure are in good agreement with experimental results.
[1] Marrink S.J.; Risselada H.J.; Yefimov S.; Tieleman D.P.; de Vries A.H. J. Chem. Phys. B, 2007, 111, p 7812.