Regensburg 2013 – wissenschaftliches Programm

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CPP: Fachverband Chemische Physik und Polymerphysik

CPP 34: Poster: Wetting, Micro and Nano Fluidics

CPP 34.18: Poster

Mittwoch, 13. März 2013, 16:30–18:30, Poster C

Hydrogel driven microfluidics in structured paper substrates — •Robert Niedl and Carsten Beta — Institute of Physics and Astronomy, University of Potsdam, Germany

Many clinical tests require a purified analyte in combination with freshly prepared biological solutions. Under working conditions far away from standard clinical laboratories, e.g. in developing countries, such prerequisites are often difficult to establish. Here, we present a system that offers a solution to such problems. We extend the recently developed concept of paper-based microfluidics by incorporating a hydrogel into the paper device. The swollen hydrogel stores a defined volume of fluid on the sensor substrate. Through a thermally driven collaps of the hydrogel, the liquid is released to drive the fluidic system without any pumps or other sophisticated equipment. Sensitive chemicals deposed in initially dry sections of the paper substrate can be dissolved and transported across fluidic channels imprinted in the paper substrate. In this way, different chemicals can be supplied in a well-controlled and timely fashion to a reaction area, in which a specific assay may be performed. We demonstrate this concept by implementing a standard glucose test in this type of hydrogel-driven paper-fluidic device.