Berlin 2014 – wissenschaftliches Programm

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Q: Fachverband Quantenoptik und Photonik

Q 30: Poster: Photonics, laser development and applications, ultrashort laser pulses, quantum effects

Q 30.27: Poster

Dienstag, 18. März 2014, 16:30–18:30, Spree-Palais

Polymer DFB laser with hydrogel recognition layer for label-free biosensing — •Esmaeil Heydari1,2, Jens Buller1, Erik Wischerhoff2, Sebastian Döring1,2, Anna Sobolewska2, Regina Rosenhauer2, Andre Laschewsky1,2, and Joachim Stumpe1,21University of Potsdam, Faculty of Science, Karl-Liebknecht-Str. 24-25, 14476 Potsdam, Germany — 2Fraunhofer IAP, Geiselbergstr. 69, 14476 Potsdam, Germany

Over the last decades, different optical techniques have been developed for label-free biosensing due to the increasing demands for sensitive, high throughput and cost-effective biosensors. Label-free biosensors based on passive optical resonators such as microrings, microspheres, photonic crystals and plasmon resonances can provide high resolution or sensitivity for the detection of analyte molecules. However, active optical cavity biosensors have been attracted more attention due to their capability to produce their own resonance light while they exhibit superior characteristics in comparison to the passive counterparts. In this work, a polymer DFB laser with a hydrogel recognition layer was developed in order to realize an all-polymer active optical cavity sensor for high throughput and disposable label-free biosensing. This laser biosensor is a stack of three functional layers including a holographic grating with low refractive index as optical resonator, a semiconducting polymer layer with high refractive index as gain medium and a biofunctional hydrogel layer as a receptor unit. The avidin-biotin interaction was implemented as a primarily model in order to demonstrate the capability of this biosensor to perform label-free detection.

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