Mainz 2014 – wissenschaftliches Programm
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ST: Fachverband Strahlen- und Medizinphysik
ST 1: Radiation Therapy & Dosimetry
ST 1.1: Vortrag
Montag, 24. März 2014, 16:45–17:00, RW 2
Fragmentation of DNA constituents after electron impact ionization — •Benedikt Rudek1, Alexander Arndt1, Woon Yong Baek1, Marion Ute Bug1,2, and Hans Rabus1 — 1Physikalisch-Technische Bundesanstalt (PTB), Braunschweig, Germany — 2Centre for Medical Radiation Physics (CMRP), University of Wollongong, Wollongong, Australia
Ionizing radiation induces tissue damage in many ways. Damage from electron impact ionization is particularly important since electrons do not only occur as primary incident particles but also in secondary emission accompanying ion impact, photo absorption and Compton scattering. While the probability of initial radiation interaction by electrons is mainly determined by the ionization cross section, the fragmentation pattern of the ionized molecules determines the extent of the radiation damage. In this work, the fragmentation of DNA constituents after electron impact ionization is investigated as a part of the European BioQuaRT project [1], which aims at determining the physical properties of ionizing particle track structure and its consequences.
The presentation will introduce the experimental setup (target preparation, electron ionization and fragment detection) and summarize energy dependent fragmentation cross sections for an energy range starting from the ionization threshold up to several hundred electron volts.
[1] http://www.ptb.de/emrp/bioquart.html