Dresden 2017 – wissenschaftliches Programm
CPP 22.6: Vortrag
Dienstag, 21. März 2017, 10:45–11:00, ZEU 250
A novel route towards entropic polymer separation — •Paolo Malgaretti — Max Planck Institute for Intelligent Systems, Heisenbergstr. 3 70569 Stuttgart Germany
Many biological processes such as viral infection, DNA transport through membranes and gene transferring between bacteria involve the translocation of bio-polymer through nano-channels and nano-pores. Moreover, technological applications such as polymer separation, DNA sequencing, and protein sensing, rely on the translocation of polymer through restrictions.
Up to now, much attention has been payed to the case of polymers translocating through pores whose half-section is comparable to the monomer size. In contrast to this, we are concerned with the case of a polymer translocating through channels, whose cross section is larger than the size of a single monomer, yet comparable to the size of the overall gyration radius of the polymer.
In such a regime a novel dynamical scenario occurs and it appears a non-monotonous dependence of polymer translocation velocity as a function of polymer size, a feature that can be exploited for polymer separation. I will show that these numerical results can be rationalized on the basis of a simplified model that reduces the problem of polymer translocation through varying-section channels to that of a point-like particle under the action of an effective potential.