Berlin 2018 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 15: Postersession III

BP 15.1: Poster

Dienstag, 13. März 2018, 14:00–16:00, Poster B

Microcapsule suspension characterisation and manipulation — •Pierre-Yves Gires — Universität Bayreuth Experimentalphysik I Universitätsstraße 30 95447 Bayreuth

Microcapsules, as submillimetric droplets embedded within a membrane, are present both in natural and artificial suspensions (e.g. cells and drug vectors in blood circulation, microalgae in algaculture). Improvements in both their characterisation and manipulation can lead for instance to better drug vectorisation or bioenergy harvesting. Three separate studies are presented, illustrating how the coupling of microfluidic tools with theoretical analysis, including if necessary numerical simulations, allows progress in this field. First, at the cell scale, the monitoring of capsule deformations in a microfluidic channel permits to characterise the membrane viscoelastic properties of cross-linked albumin microcapsules [1]. Then, a comparison between measured and simulated hydrodynamic interactions brings further insight into the origin of hydrodynamic diffusion of vesicles suspensions [2]. Last, the coupling of a thin plate subwavelength resonance with bubble secondary acoustic amplification allows to design a promising acoustofluidic device, for both locally concentrating and depleting microcapsule suspensions [3].

[1] Gires et al. "Pairwise hydrodynamic interactions and diffusion in a vesicle suspension." Physics of Fluids 26.1 (2014): 013304. [2] Gires et al. "Transient behavior and relaxation of microcapsules with a cross-linked human serum albumin membrane." Journal of the mechanical behavior of biomedical materials 58 (2016): 2-10. [3] to be published