Berlin 2018 – wissenschaftliches Programm
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BP: Fachverband Biologische Physik
BP 15: Postersession III
BP 15.89: Poster
Dienstag, 13. März 2018, 14:00–16:00, Poster B
Layer-by-layer assembled micro-motors for controlled drug release — Tao Huang1, Larysa Baraban1, and •Gianaurelio Cuniberti1,2 — 1Institute of Materials Science and Max Bergmann Center of Biomaterials Dresden, TU Dresden, Dresden, Germany — 2Center for advancing electronics Dresden, cfaed, Dresden
Micro-motor is a micro-scale device, capable of autonomous motion in liquid environment and having potential to find multiple applications in biomedicine.1 Here we present the light-driven micro-motors fabricated using different techniques combined, i.e. controlled template-assisted layer-by-layer (LBL) molecular assembly and electrodeposition of metals. Layer-by-layer assembled multilayer provide excellent delivery capacities and can also respond to various stimuli for controllable encapsulation and release of drugs. Composite top layer of the particles, fabricated by LBL technique represents the ideal container for drug loading and controlled release. Diverse geometries of micro-motors, including rod-like and spherical will be designed, and decorated with the biocompatible outer layer. Finally, we plan to investigate the efficiency of the micromotors for the real-time drug release during in-vitro assays.
1.*J. A. Spudich, Science, 2011, 331, 1143-1144.