Regensburg 2019 – wissenschaftliches Programm

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CPP: Fachverband Chemische Physik und Polymerphysik

CPP 25: Poster Session II

CPP 25.49: Poster

Dienstag, 2. April 2019, 14:00–16:00, Poster B1

Preferential binding of salts to pNiPAM and its monomer — •Jakub Polák, Adam Kovalčík, Pavel Vrbka, Daniel Ondo, Vladimír Palivec, and Jan Heyda — Department of Physical Chemistry, University of Chemistry and Technology, Prague, Czech Republic

Over past decade investigation of salt specific effects on biomolecules attracted a lot of experimental, computational and theoretical attention. However, the direct quantitative thermodynamic characterization is still poor. In this contribution we measure a preferential binding coefficient of salts to a well established model biomolecule, poly-N-isopropyl-acrylamide (pNiPAM). The pNiPAM-salt interaction is determined in equilibrium dialysis experiments. The results are supplemented by vapor pressure osmometry experiments of NiPAM, in which salt-monomer interactions at dilute conditions were determined. Finally, in combination with density measurements and upon application of theory of solution the thermodynamically relevant basic ingredients, Kirkwood-Buff integrals, were determined.