Dresden 2020 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 10: Poster III

BP 10.15: Poster

Montag, 16. März 2020, 17:30–19:30, P2/3OG

Cryo Scanning Electron Microscopy investigations on penetration of Titanium dioxide particles in human skin — •Hanna-Friederike Poggemann1, René Gustus1, and Wolfgang Maus-Friedrichs1,21Clausthal Centre of Material Science, Agricolastraße 2, 38678 Clausthal-Zellerfeld, Germany — 2Institute of Energy Research and Physical Technology, Leibnizstraße 4, 38678 Clausthal-Zellerfeld, Germany

Titanium dioxide nanoparticles can be found in a lot of cosmetically products as for example sunscreen. Titanium dioxide (TiO2) is not toxic for humans in micrometer size but the Nano sized particles have different material properties. TiO2 nanoparticles are for example photocatalytic active and so able to damage human cells if they get in to the living dermal layers. Previous studies have pointed out that most particles cannot penetrate the topmost dermal layer, the stratum corneum. Accordingly only a small amount of the TiO2 gets into the living cell area. But several studies also underlined the necessity of further research especially in the case of previously damaged skin. (According to actual statistics 14 % of all children und up to 3 % of the adults in Germany suffer from neurodermatitis and particularly for those persons it is inevitable to use sunscreen on their skin) In this regard we analyzed the TiO2 nanoparticles of commercially available sunscreens in our FE-SEM by SEM and EDX. Furthermore we examined samples of human skin with and without sunscreen treatment by Cryo-SEM and Focused Ion Beam to prove that out method is appropriate for continuing research on this subject.

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