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BP: Fachverband Biologische Physik
BP 32: Focus Session: Nonlinear Dynamics of the Heart I (joint session DY/BP)
BP 32.9: Vortrag
Donnerstag, 19. März 2020, 12:15–12:30, ZEU 118
Synchronization-based reconstruction of the electrical dynamics of the heart — •Baltasar Rüchardt1,3, Jochen Bröcker4, Stefan Luther1,2,3, and Ulrich Parlitz1,2,3 — 1Max Planck Institute for Dynamics and Self-Organization, Göttingen, Germany — 2Georg-August-Universität Göttingen, Institute for Nonlinear Dynamics, Göttingen, Germany — 3German Center for Cardiovascular Research (partnersite Göttingen), Göttingen, Germany — 4University of Reading, Reading, UK
For more than a century, the electrocardiogram (ECG) is the standard diagnostic tool to assess cardiac electrophysiological function. The relation between the electrical excitation of the heart and the electrical potential on the surface of the body is well understood. The reconstruction of the source distribution on the heart from given ECG measurements is challenging, because information is lost when the electrical signal travels through the body in a diffusion-like process. This problem is called inverse problem of electrocardiography.
The standard methods to handle this loss are regularization methods which impose pre-defined assumptions on the problem until a solution can be found. This can exclude the true solution and, in general, does not rely on information of the underlying dynamical processes. In contrast, we show the reconstruction of the electrical state of the heart from sensor signals with reduced spatial information by means of synchronization, based on a model of the spatial-temporal electrical dynamics. We show this for a 2D excitable media heart tissue model and discuss the application to three dimensions.