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CPP: Fachverband Chemische Physik und Polymerphysik
CPP 85: Focus: Polymers under confinement I
CPP 85.8: Vortrag
Donnerstag, 19. März 2020, 12:15–12:30, ZEU 222
Structure and Dynamics of Single-Chain Nanoparticles in Crowded Environments: A Combined SANS & NSE Study — •Timo Brändel1, Paula Malo de Molina2, Julian Oberdisse3, Ingo Hoffmann4, Lionel Porcar4, Josetxo Pomposo2, Arantxa Arbe2, and Juan Colmenero1,2 — 1Donostia International Physics Center, San Sebastian, Spain — 2Centro de Fisica de Materiales, San Sebastian, Spain — 3Laboratoire Charles Coulomb, Montpellier, France — 4Institut Laue-Langevin, Grenoble, France
Very recently, single-chain nanoparticles (SCNP) have been granted lots of attention in different fields of physical and chemical science. Due to their sparse-like structure, SCNP are often considered as versatile model-systems for a very interesting class of proteins, namely intrinsically disordered proteins (IDP). The synthesis of SCNP is carried out by intra-molecular crosslinking of single polymer chains by various cross-linking reactions. Therefore, SCNP are usually synthesized and investigated in strongly diluted solutions, but IDP exist rather under crowded conditions like most proteins. Hence, the effect of macromolecular crowding on SCNP is very important. Our study uses the outstanding possibilities of neutron scattering to investigate the effect of crowding on the structure and dynamics of SCNP. To address this issue, PS based SCNP are investigated in a completely contrast-matched matrix of deuterated linear PS chains by means of SANS and NSE. Important effects of the crowded environment on structural properties of the SCNP are observable and the internal dynamics are considerably slowed down compared to the dilute state.