Heidelberg 2022 – wissenschaftliches Programm

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PV: Plenarvorträge

PV I

PV I: Plenarvortrag

Montag, 21. März 2022, 11:40–12:25, Audimax

Making uncertainty certain?: Proton therapy, range and in-vivo verification. — •Tony Lomax — WPTA/140 Forschungsstrasse 111 5232 Villigen PSI Schweiz

Proton therapy (RT) is an increasingly important weapon against cancer. By controlling proton energy, and thus proton range, the dose can be concentrated in tumour more effectively than with conventional radiotherapy with photons. However, although proton ranges in water can be determined with sub-millimeter precision, the story in the patient can be quite different due to uncertainties in CT data of the patient, positioning inaccuracies and anatomical changes of the patient during the treatment course. As such, in vivo range uncertainty is one of the major challenges for proton therapy. Consequently, methods such as proton CT/probes, PET activation and prompt gamma imaging are being proposed and developed for direct and in vivo imaging of proton range. This presentation will review and compare each of these, both from their technical practicality and potential clinical impact.