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BP: Fachverband Biologische Physik

BP 9: Bioimaging

BP 9.11: Prize Talk

Tuesday, September 6, 2022, 12:30–13:00, H16

Super-resolution STED and MINFLUX Nanoscopes by Abberior Instruments — •Gerald Donnert — Abberior Instruments GmbH, Göttingen, Germany — Laureate of the Technology-Transfer-Prize 2022

Abberior Instruments GmbH was founded 10 years ago from the laboratory of Nobel Laureate Stefan Hell at the Max Planck Institute in Göttingen. In 2022, Abberior Instruments was awarded the Technology Transfer Prize of the German Physical Society (DPG).

Abberior Instruments develops and markets super-resolution light microscopes, namely confocal plus STED microscopes and MINFLUX microscopes. The latter are the latest generation of super-resolution instruments with resolutions down to the molecular level, i.e. 1 nm resolution; unrivaled in resolution today. Understanding life at the molecular level - both in terms of structure and dynamics - is a human dream and is becoming feasible with the latest generation of super-resolution instruments with multicolor capabilities. We expect to soon gain new insights into the dynamic structural changes of e.g. protein machines in living cells.

In this talk, I will present the latest imaging and tracking results with our super-resolution STED and MINFLUX nanoscopes, such as single-particle tracking of lipids in lipid membranes, the structure of nuclear pore complex (NPC) subunits, and the nanoscale assembly of proteins in neuronal synapses.