Regensburg 2022 – wissenschaftliches Programm

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CPP: Fachverband Chemische Physik und Polymerphysik

CPP 5: Wetting, Droplets and Microfluidics (joint session DY/CPP)

CPP 5.7: Vortrag

Montag, 5. September 2022, 11:45–12:00, H19

Using feedback-controlled thermoviscous flows to precisely position microparticles — •Elena Erben, Antonio Minopoli, Nicola Maghelli, Benjamin Seelbinder, Iliya D. Stoev, Sergei Klykov, and Moritz Kreysing — Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

Optical positioning of microscale objects has proven key for advancing fundamental biological research and holds great potential for other disciplines as well. The most widely used among these methods are optical tweezers which enable the precise control and manipulation of multiple particles. However, they require probes of high refractive index contrast and low absorption and exclude the use of photosensitive samples. Here we present a novel optofluidic technique that leverages optical-control capabilities and the gentle nature of hydrodynamic flows, thus lifting the aforementioned constraints. Our approach is based on optically-induced thermoviscous flows generated by the repeated scanning of a moderately heating infrared laser beam [1]. We have combined thermoviscous flows with feedback control to confine micron-sized particles with a precision of up to 24 nm without exposing them directly to laser light [2]. Recently, we extended this approach beyond single-object manipulation to further enable simultaneous control of multiple particles. With this contribution, we furthermore discuss combinations with implicit force sensing [3] and the potential for future application in and beyond the life science sector.

[1] Weinert et al., Phys. Rev. Lett., 2008; [2] Erben et al., Opt. Express, 2021; [3] Stoev et al., eLight, 2021.