Regensburg 2007 – wissenschaftliches Programm

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CPP: Fachverband Chemische Physik und Polymerphysik

CPP 20: POSTER: Biological Systems + New Materials

CPP 20.27: Poster

Mittwoch, 28. März 2007, 16:00–18:30, Poster B

Tuning surface chemistry of thin PEO films by control of morphology — •Evelyn Meyer and Hans-Georg Braun — Leibniz Institut für Polymerforschung Dresden, Max Bergmann Center of Biomaterials, D-01069 Dresden, Hohe Strasse 6

Ultrathin polyethyleneoxide (PEO) layers are of great importance as protein resistant coatings to avoid nonspecific protein adsorption. The controlled introduction of chemical groups (NH₂) into PEO layers allows a specific immobilization of proteins. Depending on the solution concentration PEO films, prepared by dip-coating, crystallize in unilamella or multiamellae morphologies. Chain length of PEO molecules and interaction of the amino-terminated PEO with the surface influence growth morphologies and distribution of amino groups on the lamella surface and consequently the grafting density of biomolecules attached to the lamella surface. The water soluble morphological PEO units can be immobilized at the surface by electron beam lithography. The arrangement of reactive amino groups within the morphological entities can be checked by selective fluorescence staining and fluorescence microscopy.