Regensburg 2022 – wissenschaftliches Programm
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HL: Fachverband Halbleiterphysik
HL 28: Organic Semiconductors 1
HL 28.1: Vortrag
Donnerstag, 8. September 2022, 09:30–09:45, H34
Dual-color organic LEDs for on demand activation and inhibition of cellular activity — •Giuseppe Ciccone1, Ilenia Meloni2, Rodrigo Gaston Fernandez Lahore3, Hans Kleeman1, Peter Hegemann3, Karl Leo1, and Caroline Murawski2 — 1Dresden Integrated Center for Applied Physics and Photonic Materials (IAPP) and Institute for Applied Physics, Technische Universität Dresden, Dresden, Germany. — 2Kurt-Schwabe-Institut für Mess- und Sensortechnik Meinsberg e.V., Waldheim, Germany — 3Institute for Biology, Experimental Biophysics, Humboldt-Universität zu Berlin, Berlin, Germany
Optical stimulation of light sensitive proteins in neurons allows optogenetics to stimulate and probe cellular activity with high spatial and temporal resolution. Multiple light sources with different wavelengths are usually required to stimulate light-sensitive proteins that combine a cation-conducting and an anion-conducting channel. Here, we present two stacked OLED architectures that can emit light with two different emission colors from the same pixel, addressing the single domains of bidirectional ion channels expressed in Drosophila melanogaster larvae and ND7/23 cells with one single, organic device. Tuning of microcavities allowed us to well match the OLED emission spectra to the activation spectra of the combined photo-sensitive proteins BiPOLES and BiPOLES-ChRmine. Our work shows that OLEDs can provide narrowband light emission with minimal crosstalk between sub-pixels, enabling us to switch between optogenetic activation and inhibition of living systems with a single device.